Overarching
Complications

Thalassemia can cause potentially life-threatening complications1-3

Flow chart showing different drivers of thalassemia and how they can cause potentially life-threatening complications
Lightbulb with question mark representing info

Unmanaged ineffective erythropoiesis and chronic hemolysis can lead to anemia, which may lead to severe complications, such as organ damage.1-3

Look closer into clinical data on complications associated with thalassemia

NTD Alpha‑Thalassemia
ComplicationsNTD Beta‑Thalassemia
ComplicationsTD Thalassemia
Complications

References:

1. Musallam KM et al; International Working Group on Thalassemia (IWG-THAL). Am J Hematol. 2022;97(2):E78-E80. doi:10.1002/ajh.26428 2. Amid A et al, eds. Guidelines for the Management of α-Thalassaemia. Thalassaemia International Federation; 2023. 3. Taher AT et al. Guidelines for the Management of Non–Transfusion-Dependent β-Thalassaemia. 3rd ed. Thalassaemia International Federation; 2023. 4. Cappellini MD et al, eds. 2021 Guidelines for the Management of Transfusion Dependent Thalassaemia (TDT). 4th ed. Thalassaemia International Federation; 2021.